Disease Control and Elimination (DCE)
The Disease Control & Elimination Theme’s scientific strategy focuses on investigating the interactions between hosts, pathogens and vectors, and evaluating interventions aimed at interrupting transmission and/or reducing the disease burden. Its research portfolio includes diseases of public health importance in West Africa at different stages of control or elimination, e.g. malaria, bacterial diseases, hepatitis B.
The Nutrition Theme aims at understanding the pathophysiology of diet-disease interactions in order to accelerate the development of more effective next-generation community and clinical interventions. Examples are the studies on iron regulation and relation with infectious diseases such as malaria and bacterial infections; and those on the peri-conceptional diet and the epigenetically-mediated adverse outcomes.
Vaccines and Immunity (VIT)
The Vaccines & Immunity Theme thrives to understand the ontogeny of immunity to inform the design of vaccines and maximise their impact. Through laboratory science and clinical trials, the theme’s aim is to contribute to the evidence based development and deployment of vaccines. The theme also undertakes a series of translational and more fundamental immunological studies aiming at understanding the development of the immune system in infancy, particularly in the context of bacterial colonisation and infectious diseases. Its TB research focuses on the identification of correlates of protection in adults and children in order to ultimately inform TB vaccine design.