30 May 2019
Staphylococcus aureus (S. aureus) is a major human pathogen with several virulence factors.
An 11-Year period Retrospective Pilot Study led by Saffiatou Darboe showed that PVL-SA strains accounted for 61.4% (180/293) of S. aureus isolates. PVL prevalence was high in both Gambian bacteraemia and SSTIs S. aureus strains. Antimicrobial resistance was low and included chloramphenicol (4.8%), cefoxitin (2.4%), ciprofloxacin (3.8%), erythromycin (8.9%), gentamicin (5.5%) penicillin (92.5%), tetracycline (41.0%), and sulfamethoxazole-trimethoprim (24.2%). There was no association of PVL with antimicrobial resistance.
A retrospective analysis was performed to investigate the prevalence of one such virulence factor (PVL) amongst clinical S. aureus samples. We found a high prevalence in our setting but antimicrobial resistance including methicillin resistance was low.
The report has been published in the Frontiers Media Journal
Congratulations to Saffie and team.